Which of the following groups formed rifle clubs known as red shirts to intimidate voters?

This article is from the Encyclopedia of North Carolina edited by William S. Powell. Copyright © 2006 by the University of North Carolina Press. Used by permission of the publisher. For personal use and not for further distribution. Please submit permission requests for other use directly to the publisher.

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The Red Shirts were a white supremacist terrorist group and intimidation wing of the Democratic Party in North Carolina during the late nineteenth century. They were active in the state elections of 1898 and 1900 and their violence impacted the outcome of these elections. The Red Shirts received their name from loose red tunics worn as uniforms. The costumes was derived from the South Carolina Red Shirts, another white supremacy group that sought to end Republican Reconstruction in that state in the 1870s.

The Red Shirts appear to have attracted men from various economic classes; well-known ministers, for example, led their processions. Prominent Red Shirts included future congressman Claude Kitchin and future governor Cameron Morrison.

Which of the following groups formed rifle clubs known as red shirts to intimidate voters?

In 1898, the political strategy of the North Carolina Democratic Party, which had lost power to Populist and Republican Fusionists in 1894, was to regain control of the General Assembly by emphasizing the danger of African American office holding and voting. Early in the campaign, Democratic leaders recognized that success would depend on more than logical persuasion. As a result, they used Red Shirts to threaten and intimidate black and white Populists and Republicans.

The Red Shirts and their violence played a substantial role in the 1898 election, which produced the first Democratic General Assembly since 1893. Red Shirts were organized as groups of mounted men, often masked, who carried pistols, rifles, and shotguns. Centered in the eastern part of the state, they made threats of death and physical or economic harm to political opponents. Red Shirts broke up political meetings and prevented Fusionist candidates from speaking. They also engaged in direct forms of violence including beatings and whippings of Black and African American people, assaults on candidates, and murder. While roaming in rural areas, they shot into the residences of their political opponents. On election day 1898, Red Shirts prevented non-Democrats from getting to polls. One gang mobbed the train of Republican governor Daniel L. Russell Jr. at Hamlet, while others paraded in front of the governor's mansion.

In 1899, Democratic legislators planned to guarantee the party's continued rule by formally disfranchising its opponents. The device for this grip on state government was a constitutional amendment limiting the right to vote, for which an election was to be held in August 1900.

Once again Red Shirts were called upon for violence and intimidation. In Smithfield, they attacked a Populist speaker's platform. Red Shirts beat and threatened Populists, dragged black people from their homes and assaulted them, and threatened opposition voters with death if they appeared at polls. In 1900 they collected large stores of arms, harassed opposition orators, and stole Fusionist mail. Populist U.S. senator Marion Butler was assaulted by Red Shirts when he tried to leave a train in eastern North Carolina. In contrast, Red Shirts escorted their Democratic heroes, including future governor Charles B. Aycock. Advertising the muscle of white supremacy, they appeared frequently at Aycock's rallies in the eastern part of the state. Rather than an accidental by-product of white supremacy fervor, Red Shirt violence was planned by Democratic officials. It is likely, for instance, that campaign funds raised by the state party were used to hire Red Shirts and to buy alcohol for them.

The bloody campaigns of intimidation were successful. Voting results indicate fraud and massive declines in black turnout. Democrats, including Josephus Daniels, Furnifold M. Simmons, and Aycock, justified the admittedly criminal acts of 1898 and 1900 as necessary given the "evil" of black political participation. Red Shirts' activities demonstrated the expediency of the politics of white supremacy, the limited appeal of universal democracy among North Carolina's early twentieth-century leaders, and the persistence of violence as a political tactic.

Political movements and parties

Encyclopedia of North Carolina, University of North Carolina Press.

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Ubiquitylation is a post-translational modification that influences a wide variety of cellular processes including protein degradation, protein subcellular localization, cell cycle progression, transcription, and DNA damage repair. Covalent attachment of the small ubiquitin molecule to a target protein involves the sequential action of three enzymes (E1, E2, and E3). In this process, substrate specificity is conferred by the E3 ligase. Our work has focused on the function of one such E3 ubiquitin ligase, WWP1. Known targets of WWP1 include cell cycle proteins, tumor suppressors, and transcription factors that promote differentiation of mesenchymal stem cells to the osteoid lineage. Recently, we have identified a novel target of WWP1 – the gap junction protein connexin (CX) 43. In particular, we found that mice overexpressing WWP1 had a 90% reduction in CX43 within the myocardium and died from ventricular arrhythmias as a consequence. CX43 is a transmembrane protein that oligomerizes to form intercellular channels which facilitate communication between adjacent cells via the transfer of small molecules. This metabolic and electrical coupling of adjacent cells plays a vital role in almost all cellular processes including growth and differentiation, cell division, and homeostasis as well as in electroconduction of the heart. Therefore, it is not surprising that CX43 is broadly expressed in nearly every cell type, and it is likely that there are commonalities underlying the regulation of CX43 in all cells that express it. Of particular interest is the fact that CX43 has a remarkably short half-life for an integral membrane protein (on the order of 1-5 hours) in all cell types examined.

To investigate the molecular mechanisms involved in CX43 turnover, we used an established tissue culture system to examine the effects of changes in expression of WWP1 on the stability and subcellular localization of CX43. We found that CX43 could co-immunoprecipitate with WWP1, and this interaction was dependent on the PPXY motif of CX43. This association promoted the K27- and K29-linked polyubiquitylation of CX43 by WWP1. Co-immunoprecipitation of WWP1 with CX43 and subsequent ubiquitylation of CX43 was enhanced in the presence of phorbol 12-myristate 13-acetate (PMA) which has been reported to induce mitogen activated protein kinase (MAPK)-dependent phosphorylation and subsequent internalization of CX43 from the cell membrane to the early endosomes. WWP1-mediated ubiquitylation was found to destabilize CX43, as the overexpression of wild type WWP1 in HeLa-CX43 cells reduced the half-life of CX43 from 2 hours to less than 1 hour, while a mutant version of WWP1 lacking ubiquitin ligase activity (C866S) had no significant effect on the stability of CX43. The increased turnover of CX43 associated with the overexpression of WWP1 also significantly reduced gap junction-mediated intercellular communication. Further investigation of the role of WWP1-mediated ubiquitylation on CX43 trafficking revealed that the ligase activity of WWP1 promoted trafficking of WWP1 from the early endosome to the late endosome with subsequent delivery to the lysosome for degradation. These observations were corroborated when endogenous WWP1 was knocked down using a siRNA pool that targets WWP1. Specifically, loss of WWP1 was associated with increased levels of CX43 on the plasma membrane and with decreased trafficking of CX43 from the early endosome to the late endosome. Instead, with WWP1 knockdown, increased co-localization of CX43 with the recycling endosome marker RAB11 was noted. These data, in conjunction with our overexpression studies, suggest that WWP1 ubiquitylates CX43 in the early endosome, and this signal is required for trafficking to the lysosome for degradation. In the absence of functional WWP1, CX43 is trafficked back to the plasma membrane via an endogenous recycling pathway whose existence hitherto has been sparsely described in the literature. Collectively, this study has identified a novel role for WWP1-mediated ubiquitylation in the trafficking and lysosomal degradation of CX43 involving an atypical ubiquitin linkage. Gap junction dysregulation is associated numerous pathological conditions including arrhythmia, skin defects, cataracts and carcinogenesis. Therefore, studies like this one that elucidate the molecular mechanisms underlying the regulation of CX43 will greatly contribute towards the development of novel therapeutics.

Abreha, M. H.(2014). Molecular Mechanisms of Gap Junction Regulation by the E3 Ubiquitin Ligase WWP1. (Doctoral dissertation). Retrieved from https://scholarcommons.sc.edu/etd/2984


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The non-linear elastodynamics of a flat plate subjected to low velocity foreign body impacts is studied, resembling the space debris impacts on the space structure. The work is based on a central hypothesis that in addition to identifying the impact locations, the material properties of the foreign objects can also be classified using acousto-ultrasonic signals (AUS). Simultaneous localization of impact point and classification of impact object is quite challenging using existing state-of-the-art structural health monitoring (SHM) approaches. Available techniques seek to report the exact location of impact on the structure, however, the reported information is likely to have errors from nonlinearity and variability in the AUS signals due to materials, geometry, boundary conditions, wave dispersion, environmental conditions, sensor and hardware calibration etc. It is found that the frequency and speed of the guided wave generated in the plate can be quantized based on the impactor's relationship with the plate (i.e. the wave speed and the impactor's mechanical properties are coupled). In this work, in order to characterize the impact location and mechanical properties of imapctors, nonlinear transient phenomenon is empirically studied to decouple the understanding using the dominant frequency band (DFB) and Lag Index (LI) of the acousto-ultrasonic signals. Next the understanding was correlated with the elastic modulus of the impactor to predict transmitted force histories.

The proposed method presented in this thesis is especially applicable for SHM where sensors cannot be widely or randomly distributed. Thus a strategic organization and localization of the sensors is achieved by implementing the geometric configuration of Theodorous Spiral Sensor Cluster (TSSC). The performance of TSSC in characterizing the impactor types are compared with other conventional sensor clusters (e.g. square, circular, random etc.) and it is shown that the TSSC is advantageous over conventional localized sensor clusters. It was found that the TSSC provides unbiased sensor voting that boosts sensitivity towards classification of impact events. To prove the concept, a coupled field (multiphysics) finite element model (CFFEM) is developed and a series of experiments were performed. The dominant frequency band (DBF) along with a Lag Index (LI) feature extraction technique was found to be suitable for classifying the impactors. Results show that TSSC with DBF features increase the sensitivity of impactor's elastic modulus, if the covariance of the AUS from the TSSC and other conventional sensor clusters are compared. It is observe that for the impact velocity, geometric and mechanical properties studied herein, longitudinal and flexural waves are excited, and there are quantifiable differences in the Lamb wave signatures excited for different impactor materials. It is found that such differences are distinguishable only by the proposed TSSC, but not by other state-of-the-art sensor configurations used in SHM. This study will be useful for modeling an inverse problem needed for classifying impactor materials and the subsequent reconstruction of force histories via neural network or artificial intelligence.

Finally an alternative novel approach is proposed to describe the Probability Map of Impact (PMOI) over the entire structure. PMOI could serve as a read-out tool for simultaneously identifying the impact location and the type of the impactor that has impacted the structure. PMOI is intended to provide high risk areas of the space structures where the incipient damage could exist (e.g. area with PMOI > 95%) after an impact.

Agbasi, C.(2014). Classification of Low Velocity Impactors Using Spiral Sensing of Acousto-Ultrasonic Waves. (Master's thesis). Retrieved from https://scholarcommons.sc.edu/etd/2660


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Chemistry and Biochemistry

This dissertation represents our preliminary mechanistic investigations on the silylation-based kinetic resolution of secondary alcohols, and how we use that knowledge for further expansion of this methodology. Chapter 2 describes how we came up with a preliminary mechanism of our silylation-based methodology using a linear free energy relationship and a rate study. In this chapter, several para substituted triphenylsilyl chlorides were prepared that varied electronically and sterically in order to understand the substituent effects on the rate and the selectivity of the reaction. Selectivity factors and initial rates were experimentally determined for the kinetic resolution reactions with the newly designed silyl chlorides. Linear free energy relationships were found to correlate both selectivity factors and initial rates.

Chapter 3 covers our 29Si NMR studies in order to understand if a complex is forming between the catalyst (-)-tetramisole and Ph3SiCl. A variety of different techniques were used including 1H NMR titrations, 29Si NMR experiments, and 1H-29Si gHSQC 2D experiments. Finally, three different mechanisms were proposed for future study.

Chapter 4 discusses our efforts to apply the silylation-based methodology developed by the Wiskur lab to allylic alcohols, homoallylic alcohols, and 2-arylcyclohexanols. No enantiodiscrimination was obtained with allylic alcohols and homoallylic alcohols while a moderate level of selectivity was achieved with 2-arylcyclohexanols. Employing Ph3SiCl substituted in the para position with an isopropyl group in the kinetic resolution reaction of 2-arylcyclohexanol resulted in a doubling of the selectivity factor. The synthesis of various substrates and employing them in our kinetic resolution is discussed.

Chapter 5 describes the use of a polymer supported triphenylsilyl chloride in our kinetic resolution reaction. Different molecular weight polymers containing triphenylsilyl chloride were prepared and tested in the kinetic resolution of 4-chromanol. Similar selectivity factors were reported in all cases. Reaction optimization along with future work for this project is discussed.

Finally, Chapter 6 explores our attempt toward the development of a kinetic resolution of amines by transforming them into imines and employing them in an asymmetric aza-Diels-Alder reaction. Various chiral Lewis acids were attempted to achieve selectivity in the aza-Diels-Alder reaction.

AKHANI, R. K.(2014). Mechanistic Investigation of a Silylation-Based Kinetic Resolution Using Linear Free Energy Relationships and Its Application to Substrate Expansion and Polymer Supported Kinetic Resolutions. (Doctoral dissertation). Retrieved from https://scholarcommons.sc.edu/etd/2785


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Epidemiology and Biostatistics

Prostate cancer is the leading invasive malignancy and the second most common cause of cancer death among American men. Despite compelling evidence that oxidative stress, ineffective DNA damage repair, and habitually low antioxidants intake may act in tandem to influence prostate carcinogenesis, few studies have examined gene-diet interactions involving these risk factors. Even fewer studies have examined such interactions in relation to prostate cancer aggressiveness. This study investigated whether single nucleotide polymorphisms (SNPs) in DNA repair- and oxidative stress-related genes modulated associations between antioxidant intake and prostate cancer aggressiveness. We utilized data from the North Carolina-Louisiana Prostate Cancer Project (PCaP) among African-American (n = 948) and European-American (n = 1,016) men. Antioxidant intake was assessed using a food frequency questionnaire, and genotypes of 30 germline SNPs were examined. Effect modification by certain polymorphic variants were observed with some variations by race, including variants in XRCC1 (rs2854508, T > A), XPA (rs3176644, G > T), NOS3 (rs1799983, G > T), OGG1 (rs1805373, G > A) and NQO1 (rs689453, C > T). For example, significant interaction was observed between XRCC1 (rs2854508) genotype and α-tocopherol intake among African Americans and European Americans, such that among those with the TT genotype, higher α-tocopherol intake was inversely related to prostate cancer aggressiveness, while higher α-tocopherol intake was positively related to high aggressive prostate cancer among those who harbor the AA or AT genotype. A similar pattern of effect modification by XRCC1 (rs2854508) was observed for the association between γ-tocopherol and prostate cancer aggressiveness, but only among African Americans. Lower odds of high aggressive prostate cancer was observed among European Americans who possess the CT or TT genotype of NQO1 (rs689453) and had higher lycopene intake, but not European Americans with the CC genotype, and there was no evidence of effect modification among African Americans. Reduced odds and increased odds of high aggressive prostate cancer were observed with higher intakes of certain antioxidants (i.e., α-tocopherol, γ-tocopherol and lycopene) dependent on genotype, indicating potentially differential dietary recommendations based on genetic susceptibility. Because germline genotype is unalterable, these findings underscore the importance of considering genetic risk variability as part of dietary intervention strategies to identify the subgroup of men who are likely to benefit from such interventions.

Antwi, S.(2014). Single Nucleotide Polymorphisms in DNA Repair and Oxidative Stress Genes, and Their Interaction with Antioxidants on Prostate Cancer Aggressiveness. (Doctoral dissertation). Retrieved from https://scholarcommons.sc.edu/etd/2995


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Health Services and Policy Management

Considering the increasing challenge to providing access to affordable healthcare in the United States and its effect on the economy, it is critical for patients, healthcare organizations, financial institutions, and federal and state agencies to understand the impact of different organizational structures within affiliated hospitals. The objective of this study was to investigate the impact of different organizational structures within rural multi-hospital systems (MHS) on the hospitals’ financial performance and the quality of patient care. The data for this study were drawn by linking two national datasets: the 2011 American Hospital Association (AHA) Annual Survey and the 2012 American Hospital Directory (AHD). The two databases were linked via the Medicare ID Number. The AHA survey provided information on rural hospitals’ organizational structure and financial information. The AHD data, extracted from the 2012 CMS Medicare Compare National Dataset based on researchers’ specifications, provided the quality of care and financial measures for the study. The three financial measures used were 1) operating margin, 2) return on equity (ROE), and 3) days cash on hand. Furthermore, the qualityof- care indicators studied were the 30-day readmission rate and the 30-day mortality rate associated with acute myocardial infarction, heart failure, and pneumonia. Multivariate pairwise regression analysis was used to examine the relationship between the outcome

variables, financial and quality indicators, and hospitals’ organizational structure (centralized, decentralized, and moderately centralized). This study explored both the financial and quality indicators of rural MHS. There were 757 hospitals in the financial indicators pool. The financial indicators showed that there are significant variations related to days cash on hand and the types of MHS organizational structures. It was concluded that both centralized and decentralized structures had a significant relationship to days cash on hand, with decentralized MHS having the lowest days cash on hand (32.63 days). This indicates negative financial performance as more days cash on hand would suggest greater organizational stability. With respect to quality of care data, there was a total hospital pool of 233 units. The main quality indicators explored were 30-day readmission and mortality rates. These main indicators were subcategorized based on the Inpatient Quality Indicators (IQI) recommended by the Agency for Healthcare Research and Quality (AHRQ). The selected IQIs included acute myocardial infarction (AMI), congestive heart failure (CHF), and pneumonia. These IQIs were selected to gauge the quality of care of patients within hospital settings. This study found that centralized MHS had the lowest 30-Day readmission rate for CHF (23.65%). In comparison, the CHF rates were 24.75% for moderately centralized and 24.65% for decentralized MHS. Therefore, it can be concluded that when comparing decentralized, moderately-centralized, and decentralized hospitals centralized MHS provides the highest level of care for patients based on 30-day readmission rates for heart failure.

Audi, G. R.(2014). Impact of Multi-Hospital System Organizational Structure on Financial Performance and Quality of Care in Rural Hospitals. (Doctoral dissertation). Retrieved from https://scholarcommons.sc.edu/etd/2927


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The mechanics and kinematics of basement tectonic uplifts, such as the Laramide Rocky Mountain orogeny, remain poorly understood and controversial. The debate continues in part because of the limited number of well-documented present day analogs. The Garzón Massif rising between the Upper Magdalena Valley and the Llanos Basin of Colombia is an active basement uplift with well, seismic, gravity, and magnetic data available. In the past 10 Ma, PreCambrian age granitic rocks of the Garzón Massif have been uplifted and displaced against Cretaceous and Tertiary sediments of the Upper Magdalena Valley along the Garzón fault.

Aerogravimetric data calibrated by well data and 2D seismic data were used to model the geometry of the Garzón fault and the top of basement (Saldaña Fm) in 2 dimensions. The density models provide an independent estimate of fault orientation. A high density airborne gravity and magnetic survey were flown over the Garzón fault in 2000, including 2,663 line km along 1 x 5 and 1 x 4 km flight lines at elevations of 2564 and 4589 m above mean sea level.

An initial depth model was derived from the well logs, seismic reflection profile, and down-hole velocity surveys. Airborne gravity data was used to produce a Bouguer anomaly gravity map. Average rock densities were estimated from density logs, seismic velocities, and formation rock types. The regional gravity field was estimated and two-Dimensional forward models were constructed with average densities from the wells, seismic velocities, and rock types, and the initial depth model. Since the model fit is dependent on the density assumed for the Garzón Massif rocks, multiple densities and dip angles were tested.

The gravity analysis indicates that the Garzón fault is a basement thrust fault dipping at a shallow angle under the Massif. Best-fit models show a true dip of 12 to 17 degrees to the southeast. A regional density and magnetic susceptibility model of the entire Massif is consistent with dense basement rocks throughout the Garzón Massif and asymmetric loading (sedimentary basin is much deeper on NW flank – Upper Magdalena Valley). Crust thickens to the NW toward the Central Cordillera. Euler deconvolution of the magnetic field shows pronounced NE-SW trending features under the Massif which are interpreted as faults bounding a possible pre-Cambrian sedimentary rift graben. Retrodeformed 2D regional models indicate 13 km of shortening on the Garzón basement thrust in the last 12 Ma. Approximately 9 km of shortening occurred on the SE marginal basement thrust fault, probably also in the last 12 Ma. This was preceded by approximately 43 km of shortening by thin-skinned imbricate thrusting to the southeast (12 - 25 Ma). This study provides a well-documented example of an active basement uplift on low angle thrust faults.

Bakioglu, K. B.(2014). GARZÓN MASSIF BASEMENT TECTONICS: A GEOPYHYSICAL STUDY, UPPER MAGDALENA VALLEY, COLOMBIA. (Master's thesis). Retrieved from https://scholarcommons.sc.edu/etd/2782


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Educational Leadership and Policies

This study examined school founding practices of Northern and Southern women educators who initiated primary schools for blacks during the Civil War, reconstruction, and progressive eras. Case study and historical methodologies contrasted two Northern white and two Southern black school founders in the areas of backgrounds, religious affiliations, educational philosophies, political astuteness, and resourcefulness. This study relied on in-depth reviews, content analyses, and cluster analyses of archives, biographies, personal diaries, newspapers, newsletters, and secondary literature to answer the research questions. Strikingly, Rachel Crane Mather and Mary McLeod Bethune’s missionary zeal emerged from their evangelical duty of converting lives to the Christian faith. Their missionary zeal merged with curricula demonstrating religious commitment and transmitting missionary zeal to students. Political acumen was requisite for effective resourcefulness and unlimited to specific techniques.

Interestingly, social, economic, and educational limitations produced political acumen shaping resourcefulness. Further, geographic regions, while mostly isolated, did not influence the longevity of their schools; instead, geographic regions enabled Southern school founders to use aggressive approaches to secure resources for their schools. Northern school founders inherited social capital from their families, friends, and social groups while Southern school founders acquired social capital through educational experiences.

Beasley, S. F.(2014). Pioneering Women of Southern Education: A Comparative Study of Northern and Southern School Founders. (Doctoral dissertation). Retrieved from https://scholarcommons.sc.edu/etd/2781